The public are being advised not to travel this evening (Sunday, January 21) between 8pm and 12am.
Storm Isha is set to strengthen from gale to storm force with gusts of up to 80mph expected this evening.
An amber weather warning is in place, meaning there is likely to be travel disruption, damage to property and the risk of injury.
Severe gale force south to southwest winds will create large waves, leading to coastal overtopping at high tide around 8:20pm.
This will see moderate overtopping of waves and a risk of significant debris around some exposed coastal roads and promenades.
Areas affected include Shore Road (Rushen), Castletown Promenade, the northern end of Douglas Promenade, and to a lesser extent Laxey and Ramsey promenades.
Heavy rain is also expected for short periods, meaning a slight risk of localised flooding.
This evening’s flights to and from the Isle of Man have been cancelled as have Isle of Man Steam Packet sailings, including the overnight sailing from Heysham to Douglas.
The Mountain Road is also currently closed.
The National Sports Centre and the Villa Marina and its grounds will close at 7pm, while Bus Vannin is continuing to operate its services.
A spokesperson from Isle of Man Government said: 'Emergency services will monitor developments through the evening and respond to any disruption.
'Anyone who needs to report a risk to public safety should dial 999. To report non-emergency road issues, Highway Services can be contacted on 672000.
'Wind speeds are expected to drop overnight but those travelling on Monday morning should take extra care as there will be debris and standing water on roads, pavements and footpaths.'
If you wish to keep updated on the latest developments of Storm Isha, you can check out our live blog here.